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ROS1-7991
组织学诊断:

The right upper lobe resection specimens:1. (right upper lobe)Central type invasive adenocarcinoma, part of acinar adenocarcinoma, a small part of micro papillary adenocarcinoma, a small part of solid adenocarcinoma, with pleural invasion; 2. No cancer tissue was found in bronchial stump; 3、Infiltrating adenocarcinoma cells were found in the diaphragm.4、Metastatic carcinoma was found in (Group 11) lymph node (3/ 7), (left laryngeal reflux)lymph node (1 / 2), (Group 7)lymph node, (3/ 8), (Group 9) lymph node (2 / 3) and (Group 10) lymph node (2 / 5).

免疫组织化学:

CK7(++),TTF-1(++),NapsinA(++),CKH(++),ki-67(+, about 20%),P40(+,A few cells),P63(+),Vimentin(-),CK5/6(-),Syn(-),CgA(-),CD56(-).

总体检查结果:

The right upper lobectomy specimen: The volume is 12 * 9.5* 2.5cm. There were a grayish yellow mass 1cm away from the bronchial stump with the volume of 6.5 * 3.5 * 3cm. The section is grayish yellow and medium in quality. In addition, gray white nodules were found in diaphragmatic tissue with the volume of 2.5 *1.5 *1cm.

性别:F

年龄:57

家族历史 :Mother died for unknown reasons. Father is still alive

血清学检查 :Serum CEA was slightly higher and NSE was normal

手术方式 :right upper lobectomy

肿瘤大小: 6.5 * 3.5 * 3cm

疾病状态(原发/复发):primary

G:II-III

分期:T4N3M1

阶段:IVA

基因:ROS1

突变位点:PCR

突变类型:fusion

%肿瘤 :*

%坏死:*

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