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Microscopic observations:

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General observations:

1.Exploration revealed no pleural effusion or adhesions. The lung fissures were well developed. A lesion was located in the apicoposterior segment of the left upper lobe, with pleural retraction at the site of the lesion. 2.The tumor measured approximat

Pathologic diagnosis:

Left Upper Lobe Resection Specimen: 1.(Left) Lung (upper lobe): Peripheral malignant tumor. The histological and immunophenotypic features are consistent with adenosquamous carcinoma. The tumor invades the pleura. 2.Bronchial stump: No carcinoma identif

Gross examination findings:

1.Left upper lobe resection specimen measuring 20 × 11 × 2.5 cm. 2.A peripheral tumor was identified 1.5 cm from the bronchial stump, which had been previously sectioned intraoperatively, measuring 3.0 × 3.0 × 2.5 cm. 3.The cut surface appeared gray-whi

Age:67

Gender:

Surgical Date:2021.07.19

Personal History:Diagnosed with tuberculosis 6 months ago; currently on regular anti-tuberculosis therapy. History of lacunar cerebral infarction for 10 years. No history of exposure to dust, toxins, or radioactive substances.

Family history:Father deceased (cause unknown); mother and children are healthy.

Smoking and drinking history:

Tumor size:3.0cmx3.0cmx2.5cm

Histological diagnosis:Mediastinoscopy was not performed. On July 9, 2021, a bronchoscopy was conducted, and pathology from the left upper lobe biopsy revealed non–small cell lung carcinoma (NSCLC), favoring poorly differentiated squamous cell carcinoma.

Immunohistochemistry:CK5/6 (+), p40 (+), CK7 (+), CK18 (+), Ki-67 (+, focal ~60%), MLH1 (+), PMS2 (+), MSH6 (+), MSH2 (+), EMA (+), SP-B (+, few cells), TTF-1 (+, partial cells), Vimentin (−), Syn (−), CD34 (−), D2-40 (−).

Grade:II

TNM:T2aN0M0

Stage:IB

Gleason Score:/

Gleason Grade:/

Tumor content (%):0.7

Necrosis content (%):0

Treatment Regimen:Systemic chemotherapy

Disease Progression:Chemotherapy Regimen: Paclitaxel (albumin-bound): 300 mg IV on Day 1 Cisplatin: 100 mg IV on Day 1 First cycle: October 7, 2021 Planned total: 6 cycles

Follow Up:Alive

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